Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CREBBP All Species: 28.18
Human Site: T1274 Identified Species: 51.67
UniProt: Q92793 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92793 NP_001073315.1 2442 265351 T1274 F E K K K N D T L D P E P F V
Chimpanzee Pan troglodytes XP_523285 2442 265358 T1274 F E K K K N D T L D P E P F V
Rhesus Macaque Macaca mulatta XP_001095225 2442 265320 T1274 F E K K K N D T L D P E P F V
Dog Lupus familis XP_851777 2404 260682 T1239 F E K K K N D T L D P E P F V
Cat Felis silvestris
Mouse Mus musculus P45481 2441 265456 T1275 F E K K K N D T L D P E P F V
Rat Rattus norvegicus NP_596872 2444 265618 T1275 F E K K K N D T L D P E P F V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_414964 2447 266615 T1273 F E K K K N D T L D P E P F V
Frog Xenopus laevis NP_001088637 2428 264402 M1265 F E K K K N D M L D S E P F V
Zebra Danio Brachydanio rerio NP_001082924 2111 234059 T1125 V K K L G Y V T A H I W A C P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_524642 3276 340709 K1886 Q S Q T Q I K K D Q F K E M K
Honey Bee Apis mellifera XP_001122031 2606 284119 H1475 F Q E M K N D H L E L E P F V
Nematode Worm Caenorhab. elegans P34545 2056 227161 E1070 V I D Y E P F E R C K Y C M R
Sea Urchin Strong. purpuratus XP_782558 2635 288594 I1483 F C R K K N D I L E P E P M Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.9 99.4 93.9 N.A. 94.8 95.8 N.A. N.A. 88 76 61.5 N.A. 36.5 42.7 30.5 38.5
Protein Similarity: 100 99.9 99.6 95.5 N.A. 96.4 97.2 N.A. N.A. 92 83.3 68.8 N.A. 46.7 54.7 43.9 50.9
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. 100 86.6 13.3 N.A. 0 60 0 60
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 100 86.6 20 N.A. 20 80 6.6 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 8 0 0 0 8 0 0 % A
% Cys: 0 8 0 0 0 0 0 0 0 8 0 0 8 8 0 % C
% Asp: 0 0 8 0 0 0 77 0 8 62 0 0 0 0 0 % D
% Glu: 0 62 8 0 8 0 0 8 0 16 0 77 8 0 0 % E
% Phe: 77 0 0 0 0 0 8 0 0 0 8 0 0 70 0 % F
% Gly: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 8 0 8 0 0 0 0 0 % H
% Ile: 0 8 0 0 0 8 0 8 0 0 8 0 0 0 0 % I
% Lys: 0 8 70 70 77 0 8 8 0 0 8 8 0 0 8 % K
% Leu: 0 0 0 8 0 0 0 0 77 0 8 0 0 0 0 % L
% Met: 0 0 0 8 0 0 0 8 0 0 0 0 0 24 0 % M
% Asn: 0 0 0 0 0 77 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 8 0 0 0 0 62 0 77 0 8 % P
% Gln: 8 8 8 0 8 0 0 0 0 8 0 0 0 0 0 % Q
% Arg: 0 0 8 0 0 0 0 0 8 0 0 0 0 0 8 % R
% Ser: 0 8 0 0 0 0 0 0 0 0 8 0 0 0 0 % S
% Thr: 0 0 0 8 0 0 0 62 0 0 0 0 0 0 0 % T
% Val: 16 0 0 0 0 0 8 0 0 0 0 0 0 0 70 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % W
% Tyr: 0 0 0 8 0 8 0 0 0 0 0 8 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _